07/2011
BSc in Biotechnology
Licenciatura en Biotecnología
Universidad de León
07/2011
MY CV
Table Of Contents
- MY DEGREES
- MY PUBLICATIONS
- Frequency and prognostic impact of KIT and other genetic variants in indolent systemic mastocytosis – PubMed
- Bone Marrow Mast Cell Antibody-Targetable Cell Surface Protein Expression Profiles in Systemic Mastocytosis – PubMed
- Impact of somatic and germline mutations on the outcome of systemic mastocytosis – PubMed
- Characterization of CD34 + hematopoietic cells in systemic mastocytosis: Potential role in disease dissemination – PubMed
- High-throughgput phage-display screening in array format – PubMed
- Evaluation of homo- and hetero-functionally activated glass surfaces for optimized antibody arrays – PubMed
- Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome – PubMed
- Emerging Nanotechniques in Proteomics
- Protein arrays as tool for studies at the host-pathogen interface – PubMed
- Protein microarrays: technological aspects, applications and intellectual property – PubMed
- Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium – PubMed
- Data Analysis Strategies for Protein Microarrays – PubMed
- Biomarker discovery by novel sensors based on nanoproteomics approaches – PubMed
- INTERNSHIPS
- LANGUAGES
- MY SKILLS
MY DEGREES
MY PUBLICATIONS
Frequency and prognostic impact of KIT and other genetic variants in indolent systemic mastocytosis – PubMed
Indolent systemic mastocytosis (ISM) patients have a normal life expectancy, except in the 5% to 10% of cases that progress to more advanced SM (advSM), which has a significantly poorer outcome. Mutations in genes other than KIT frequently found in myeloid neoplasms have been associated with …
Bone Marrow Mast Cell Antibody-Targetable Cell Surface Protein Expression Profiles in Systemic Mastocytosis – PubMed
Despite recent therapeutic advances, systemic mastocytosis (SM) remains an incurable disease due to limited complete remission (CR) rates even after novel therapies. To date, no study has evaluated the expression on SM bone marrow mast cells (BMMC) of large panel of cell surface suitable for antibod…
Impact of somatic and germline mutations on the outcome of systemic mastocytosis – PubMed
Systemic mastocytosis (SM) is a highly heterogeneous disease with indolent and aggressive forms, with the mechanisms leading to malignant transformation still remaining to be elucidated. Here, we investigated the presence and frequency of genetic variants in 34 SM patients with multilineal KIT</i…
Characterization of CD34 + hematopoietic cells in systemic mastocytosis: Potential role in disease dissemination – PubMed
The presence of the KIT D816V mutation in PB of ISM patients is associated with (early) involvement of circulating CD34+ HPC and multiple myeloid cell subpopulations, KIT-mutated PB CD34+ HPC potentially contributing to early dissemination of the disease.
High-throughgput phage-display screening in array format – PubMed
Emerging technologies for the design and generation of human antibodies require improved approaches enabling their screening, characterization and validation. Currently, strategies based on ELISA or western blot are used to that aim. However, the ever increasing number of novel antibodies generated …
Evaluation of homo- and hetero-functionally activated glass surfaces for optimized antibody arrays – PubMed
Antibody arrays hold great promise for biomedical applications, but they are typically manufactured using chemically functionalized surfaces that still require optimization. Here, we describe novel hetero-functionally activated glass surfaces favoring oriented antibody binding for improved performan…
Surfing transcriptomic landscapes. A step beyond the annotation of chromosome 16 proteome – PubMed
The Spanish team of the Human Proteome Project (SpHPP) marked the annotation of Chr16 and data analysis as one of its priorities. Precise annotation of Chromosome 16 proteins according to C-HPP criteria is presented. Moreover, Human Body Map 2.0 RNA-Seq and Encyclopedia of DNA Elements (ENCODE) data…
Protein arrays as tool for studies at the host-pathogen interface – PubMed
Pathogens and parasites encode a wide spectrum of multifunctional proteins interacting to and modifying proteins in host cells. However, the current lack of a reliable method to unveil the protein-protein interactions (PPI) at the host-pathogen interface is retarding our understanding of many import…
Protein microarrays: technological aspects, applications and intellectual property – PubMed
Over the last decade, proteomics has undergone remarkable progress thanks to the technical advances made in the field. Improvements in the design of the protein microarrays, including more types of chemical groups for surface functionalization, new capture agents and novel detection strategies, amon…
Chromosome 19 annotations with disease speciation: a first report from the Global Research Consortium – PubMed
A first research development progress report of the Chromosome 19 Consortium with members from Sweden, Norway, Spain, United States, China and India, a part of the Chromosome-centric Human Proteome Project (C-HPP) global initiative, is presented ( http://www.c-hpp.org ). From the chromosome 19 pepti…
Data Analysis Strategies for Protein Microarrays – PubMed
Microarrays constitute a new platform which allows the discovery and characterization of proteins. According to different features, such as content, surface or detection system, there are many types of protein microarrays which can be applied for the identification of disease biomarkers and the char…
Biomarker discovery by novel sensors based on nanoproteomics approaches – PubMed
During the last years, proteomics has facilitated biomarker discovery by coupling high-throughput techniques with novel nanosensors. In the present review, we focus on the study of label-based and label-free detection systems, as well as nanotechnology approaches, indicating their advantages and app…
INTERNSHIPS
October – November 2013
September – December 2019
LANGUAGES
Bilingual Native
Nativa Bilingüe
Galego – Castellano
English – Level C1
Français – Niveau B2
Deutsch – Niveau B1
MY SKILLS
SOFT SKILLS
BASIC LAB TECHNIQUES
WRITING & CONTENT CREATION
FLOW CYTOMETRY
PROTEOMICS
BIOINFORMATICS
NEXT GENERATION SEQUECING
